NOCODEBIOASSAYPHARMACOLOGICAL RELEVENCETURN AROUND TIME
1.              CA01
Lymphocyte proliferation
a. Naïve and LPS treated lymphocytes
b. Naïve and PHA induced
c. Naïve and Con A treated lymphocytes
d. Naïve and PWA induced
e. Naïve and anti-CD3 induced
Immune modulation 4 weeks
2.              CA02NO release Immune modulation 4 weeks
3.              CA03NO scavenging Anti-oxidant, Inflammation, Pain4 weeks
4.              CA04Macrophage phagocytosisImmune modulation4 weeks
5.              CA05LTB4 release Inflammation, Pain6 weeks
6.              CA06Hepatoprotection using t-BH Liver health4 weeks
7.              CA08Histamine release Inflammation, Allergy6 weeks
8.              CA09Chromosomal aberration (OECD – 473)Safety evaluation8 weeks
9.              CA10Micronucleus (OECD – 487)Safety evaluation 8 weeks
10.          CA11Melanin release using B16Skin Tanning / Lightning4 weeks
11.          CA12PGE2 release Inflammation, Pain4 weeks
12.          CA13Insulin releaseDiabetes4 weeks
13.          CA14Collagen releaseWrinkle, Ageing6 weeks
14.          CA15TXB2 releaseInflammation, Allergy, Pain4 weeks
15.          CA16IL-1 beta inhibition +Inflammation, Allergy6 weeks
16.          CA17TNF alpha inhibition +Inflammation, Allergy6 weeks
17.          CA18AMES test (Bacterial Reverse Mutation)Safety evaluation4 weeks
18.          CA19IL-2 release (Con A induced)+Immune modulation6 weeks
19.          CA20IL-4 release (Con A induced)+Immune modulation6 weeks
20.          CA21IL-6 release (Con A induced)+Immune modulation6 weeks
21.          CA22IFN gamma release (Con A induced)+Immune modulation6 weeks
22.          CA23Neutral Red Uptake**Cytotoxicity, CC50 correlation to acute oral rodent LD50, safety evaluation4 weeks
23.          CA24Cellular antioxidant activityGeneral health, heart diseases4 weeks
24.          CA25Hepatoprotection assay against diazinon (OPC)Liver health4 weeks
25.          CA26IL-6 inhibition+ Inflammation6 weeks
26.          CA27IL-2 release (PHA induced)+ Immune modulation6 weeks
27.          CA28IL-6 release (PHA induced)+ Immune modulation6 weeks
28.          CA29IL-2 release (PWA induced)+ Immune modulation6 weeks
29.          CA30IL-6 release (PWA induced)+ Immune modulation6 weeks
30.          CA31IL-2 release (Anti CD3 induced)+ Immune modulation6 weeks
31.          CA32IL-6 release (Anti CD3 induced)+ Immune modulation6 weeks
32.          CA33IL-2 release (LPS induced)+ Immune modulation6 weeks
33.          CA34IL-6 release (LPS induced)+Immune modulation6 weeks
34.          CA35Hepatoprotection assay against Aldrin (OC) Liver health4 weeks